Occasionally I get asked how genes cause cancer. It is a very complex Subject and one I’m not capable in, but here goes. Macmillan Cancer Support also has a patient booklet on this issue.
Genes are located in each cell in our bodies. They are the instruction manual For cells to work properly and they’re written in a code called DNA. When mistakes arise in that code, genetic mutations may result.
Many regular impacts can activate gene mutations. Things like getting Older, our surroundings, smoking, sun, our hormones, obesity and our diet.
Most cancers develop following a gene mutation happens during a person’s Lifetime, in an organ where a cancer later develops. For example, gene mutations which exist in the lungs, frequently due to smoking, may lead to lung cancer later on.
Some individuals, however, inherit a gene mutation that places them in a Higher-than-average risk of getting cancer.
When a cancer happens in a family more often than in the overall population, Some people in the family may have been born using a cancer .
A few of those inherited enzymes have been identified, like Those causing Cancers of the breast, bowel, ovary and uterus.
If two or more close blood relatives on the same side of the family had the Same type of cancer and also have experienced cancer at a young age (under 50), a cancer gene can run in the family.
If this is the case for you, it’s vital to inform your physician who can make an Appointment at a genetics clinic where your family tree will be used to assess your chance of getting the disease.
With a genetics specialist you can discuss whether to have a genetic evaluation To get a cancer gene, and should you’ve got one, you can consider telling your loved ones.
This is so they could decide whether to have genetic counselling and Predictive testing to identify with an increased chance of getting cancer and who doesn’t.
Women at high risk of ovarian or breast cancer may be provided risk-reducing Treatments such as surgery or drug therapy. Surgery might involve removal of both breasts (prophylactic mastectomy) for women with the breast cancer genes BRCA1 and BRCA2.
Risk-reducing medication therapy (chemoprevention) would mean taking an Anti-oestrogen tablet daily for five years and would decrease breast cancer risk by 30%–40%. But the pills can cause unwanted side effects, so make sure you speak through the advantages and disadvantages using a breast or colon cancer specialist.
Should you find out you have cancer, then talking to your kids about it’s Rough, but so important I will write about it separately.